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1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine图片
CAS NO:4004-05-1
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议
250mg电议

产品介绍
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) 是阳离子脂质体的中性辅助脂质 (helper lipid)，与阳离子磷脂结合，提高裸 siRNA 的转染效率。
Cas No.4004-05-1
别名1,2-二油酰-SN-甘油-3-磷酰乙醇胺,DOPE
Canonical SMILESO=P(OC[C@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)(OCCN)O
分子式C41H78NO8P
分子量744.03
溶解度DMSO: 31.25 mg/mL (42.00 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA[1].

[1]. Uemura Y, et al. The efficiency of lipid nanoparticles with an original cationic lipid as a siRNA delivery system for macrophages and dendritic cells.Pharm Dev Technol. 2019 Mar;24(3):263-268.