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1,4-Naphthoquinone
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
1,4-Naphthoquinone图片
CAS NO:130-15-4
包装:100mg
市场价:495元

产品介绍
1,4-Naphthoquinone 是抑制单胺氧化酶 MAO 和 DNA 拓扑异构酶活性的潜在药效基团，DNA 拓扑异构酶活性与抗肿瘤活性相关。
Cas No.130-15-4
别名1,4-萘醌
Canonical SMILESO=C1C=CC(C2=C1C=CC=C2)=O
分子式C10H6O2
分子量158.16
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1,4-Naphthoquinone is a potential pharmacophore for inhibition of both MAO (monoamine oxidase) and DNA topoisomerase activities, this latter associated with antitumor activity[1].

[1]. Coelho-Cerqueira E, et al. Beyond topoisomerase inhibition: antitumor 1,4-naphthoquinones as potential inhibitors of human monoamine oxidase. Chem Biol Drug Des. 2014 Apr;83(4):401-10.