IrisolIDOne 是葛根花中的一种异黄酮，具有较强的保肝活性。它是一种有效的体积调节阴离子通道 (VRAC) 电流抑制剂，有高效阻断作用，IC50 为 5-13 μM。
产品描述
Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.
体内活性
Irisolidone may attenuate ethanol-induced gastritis by inhibiting the infiltration of immune cells, particularly neutrophils, through the regulation of CXCL-4 or IL-8 secretion[2].
Cas No.
2345-17-7
分子式
C17H14O6
分子量
314.29
别名
葛花苷元;尼泊尔鸢尾异黄酮
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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