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Thalidomide-O-C8-COOH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Thalidomide-O-C8-COOH图片
CAS NO:2225148-51-4
包装与价格:
包装价格(元)
100mg电议
500mg电议

产品介绍
Thalidomide-O-C8-COOH 是一种基于 Thalidomide 的,可募集 CRBN 蛋白的 Cereblon 配体。Thalidomide-O-C8-COOH 可通过 linker 与靶蛋白配体连接,形成 PROTAC 分子。
Cas No.2225148-51-4
Canonical SMILESO=C(O)CCCCCCCCOC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
分子式C22H26N2O7
分子量430.45
储存条件-20℃, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1].

[1]. Nathanael S. Gray, et al. Degraders of wee1 kinase. WO2020069105A1.