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KB02-COOH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
KB02-COOH图片
CAS NO:2375196-30-6
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议

产品介绍
KB02-COOH是泛素E3连接酶配体KB02的合成片段。KB02可用于PROTAC的合成,例如KB02-JQ1和KB02-SLF。
Cas No.2375196-30-6
Canonical SMILESO=C(O)COC1=CC2=C(N(C(CCl)=O)CCC2)C=C1
分子式C13H14ClNO4
分子量283.71
溶解度DMSO: 66.67 mg/mL (234.99 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

KB02-COOH is a fragment of synthesis of ubiquitin E3 ligase ligand KB02. KB02 can be used in the synthesis of PROTAC, such as KB02-JQ1 and KB02-SLF [1].

[1]. Zhang X, et al. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat Chem Biol. 2019 Jul;15(7):737-746.