Siramesine hydrochloride 是一种选择性 sigma-2 受体激动剂，可引发 Y 细胞的细胞死亡并在体内表现出有效的抗癌活性。Siramesine 对 sigma-2 受体具有亚纳摩尔亲和力，并且对 sigma-2 受体的选择性是 sigma-1 受体的 140 倍。

Siramesine (Lu 28-179) hydrochloride is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit a potent anticancer activity in vivo.

224177-60-0

C30H32ClFN2O

491.05

Lu 28-179 hydrochloride;西拉美新盐酸盐

DMSO:42 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years