| CAS NO: | 731862-92-3 |
| 包装: | 100mg |
| 市场价: | 1350元 |
| Cas No. | 731862-92-3 |
| 别名 | 1-(6-氨基己基)-1H-吡咯-2,5-二酮2,2,2-三氟乙酸盐 |
| Canonical SMILES | O=C(C=C1)N(CCCCCCN)C1=O.O=C(O)C(F)(F)F |
| 分子式 | C12H17F3N2O4 |
| 分子量 | 310.27 |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Mal-C6-amine (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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