CAS NO: | 66376-36-1 |
包装 | 价格(元) |
10mM (in 1mL Water) | 电议 |
100mg | 电议 |
Cas No. | 66376-36-1 |
别名 | 阿仑膦酸 |
Canonical SMILES | OC(P(O)(O)=O)(CCCN)P(O)(O)=O |
分子式 | C4H13NO7P2 |
分子量 | 249.1 |
溶解度 | Water: 8.33 mg/mL (33.44 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Alendronic acid, a bisphosphonate, is a farnesyl diphosphate synthase (FDPS) inhibitor. Alendronic acid inhibits osteoclast-mediated bone resorption. Alendronic acid shows efficacy in postmenopausal osteoporosis, malignant hypercalcemia and Paget's disease[1]. [1]. Teixeira S, et al. Alendronic Acid as Ionic Liquid: New Perspective on Osteosarcoma. Pharmaceutics. 2020 Mar 24;12(3). pii: E293. [2]. Duckworth AD, et al. Effect of Alendronic Acid on Fracture Healing: A Multicenter Randomized Placebo-Controlled Trial. J Bone Miner Res. 2019 Jun;34(6):1025-1032. |