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Propargyl-PEG3-alcohol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Propargyl-PEG3-alcohol图片
CAS NO:208827-90-1
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
Propargyl-PEG3-alcohol 是一种 PROTAC linker,属于 PEG 类。Propargyl-PEG3-OH 可用于合成一系列 PROTAC 分子。
Cas No.208827-90-1
别名丙炔基-三聚乙二醇
Canonical SMILESC#CCOCCOCCOCCO
分子式C9H16O4
分子量188.22
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Propargyl-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Andrew P. Crew, et al. Brm targeting compounds and associated methods of use. US20190300521A1.