Hederacolchiside A1 是从白头翁中分离的一种有抗利什曼原虫和抗肿瘤增殖活性的天然产物。

Hederacolchiside A1 shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacolchiside A1 shows antiproliferation activities in three cancer cell lines with the IC50 value of 2.4 uM, it exhibits a preferential cytotoxicity on a pigmented melanoma cell line. It suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway.

106577-39-3

C47H76O16

897.109

黑海常春藤苷A1;革叶常春藤皂苷 A1

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years