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THPN
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
THPN图片
CAS NO:100079-26-3
包装与价格:
包装价格(元)
5mg电议
25mg电议

产品介绍
THPN 是一种有效的 Nur77 激动剂。
Cas No.100079-26-3
Canonical SMILESCCCCCCCCC(C1=CC(O)=C(C(O)=C1)O)=O
分子式C15H22O4
分子量266.33
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Nur77 agonist. Binds Nur77 and promotes translocation of the receptor to the mitochondria resulting in autophagy in melanoma cell lines.

Wang et al (2014) Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nat.Chem.Biol. 10 133 PMID:24316735 |Li et al (2015) Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation. Nat.Chem.Biol. 11 339 PMID:25822914