CAS NO: | 524030-00-0 |
包装 | 价格(元) |
100mg | 电议 |
500mg | 电议 |
Cas No. | 524030-00-0 |
别名 | 3,6,9,12,15-五氧杂十六烷-1-硫醇 |
Canonical SMILES | COCCOCCOCCOCCOCCS |
分子式 | C11H24O5S |
分子量 | 268.37 |
储存条件 | -20°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | m-PEG5-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |