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N-(Azido-PEG3)-N-Fluorescein-PEG4-acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N-(Azido-PEG3)-N-Fluorescein-PEG4-acid图片
CAS NO:2100306-72-5
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
N-(Azido-PEG3)-N-Fluorescein-PEG4-acid是一种PROTAClinker，属于PEG类。可用于合成PROTAC分子。
Cas No.2100306-72-5
Canonical SMILESO=C(O)CCOCCOCCOCCOCCN(CCOCCOCCOCCN=[N+]=[N-])C(NC1=CC2=C(C3(C4=C(OC5=C3C=CC(O)=C5)C=C(O)C=C4)OC2=O)C=C1)=S
分子式C40H49N5O14S
分子量855.91
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-(Azido-PEG3)-N-Fluorescein-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562