您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > NH2-PEG7
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
NH2-PEG7
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NH2-PEG7图片
CAS NO:1425973-14-3
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
NH2-PEG7是一种PROTAClinker(PROTAClinker),属于PEG类。NH2-PEG7可用于PROTACPARP1降解剂iRucaparib-AP6的合成。
Cas No.1425973-14-3
别名氨基-七聚乙二醇
Canonical SMILESOCCOCCOCCOCCOCCOCCOCCN
分子式C14H31NO7
分子量325.4
溶解度DMSO: 100 mg/mL (307.31 mM); Water:< 0.1 mg/mL (insoluble)
储存条件4°C, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

NH2-PEG7 is a PROTAC linker, which refers to the PEG composition. NH2-PEG7 can be used in the synthesis of the PROTAC PARP1 degrader iRucaparib-AP6[1].

[1]. Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15(12):1223-1231.