Ilaprazole 是一种具有口服活性质子泵抑制剂,以剂量依赖性方式不可逆地抑制H+/K+-ATPase,在兔壁细胞制剂中的IC50为 6 μM。它也是一种有效的T细胞起源蛋白激酶(TOPK)抑制剂,用于胃溃疡的研究。
产品描述
Ilaprazole is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the development of reflux oesophagitis.
Cas No.
172152-36-2
分子式
C19H18N4O2S
分子量
366.44
别名
IY81149;艾普拉唑;IY 81149;IY-81149
储存和溶解度
Ethanol:12.5 mg/mL (34.11 mM),Need ultrasonic
DMSO:35 mg/mL (95.51 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years