LX-1031 是一种有效的色氨酸 5-羟化酶抑制剂。 LX-1031 减少外周5-羟色胺的合成。

LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.

LX-1031 reduces the expression of 5-HT in the duodenum, jejunum, and ileum in a dose-dependent manner, but has no effect on brain 5-HT levels in preclinical assay[1]. The average 5-HT reductions in the jejunum relative to control are appr 33, 51, and 66%

945976-76-1

C28H25F3N4O4

538.52

DMSO:30mg/mL (55.71 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years