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N-Boc-piperazine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-Boc-piperazine图片
CAS NO:57260-71-6
包装:500mg
市场价:315元

产品介绍
N-Boc-piperazine 是一种 PROTAC linker,属于 Alkyl/ether 类。可用于合成 PROTAC PD-1/PD-L1 degrader-1 。
Cas No.57260-71-6
别名1-叔丁氧羰基哌嗪
Canonical SMILESO=C(OC(C)(C)C)N1CCNCC1
分子式C9H18N2O2
分子量186.25
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 [1].

[1]. Binbin Cheng, et al. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.