| CAS NO: | 292843-75-5 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
Biotin-PEG2-C2-iodoacetamide 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。
| Cas No. | 292843-75-5 |
| Canonical SMILES | O=C(NCCOCCOCCNC(CI)=O)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O |
| 分子式 | C18H31IN4O5S |
| 分子量 | 542.43 |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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