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PEG3-C4-OBn
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PEG3-C4-OBn图片
CAS NO:2381196-79-6
包装与价格:
包装价格(元)
Free Sample (0.1-0.5mg)电议
500mg电议
1g电议
5g电议

产品介绍
PEG3-C4-OBn 是一种 PEG 类的 PROTAC 连接桥。PEG3-C4-OBn 可用于合成 PROTAC SGK3 degrader-1 。PROTAC SGK3 degrader-1 是一种 PROTAC,专门降解 SGK3。
Cas No.2381196-79-6
Canonical SMILESOCCOCCOCCCCCCOCC1=CC=CC=C1
分子式C17H28O4
分子量296.4
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. PEG3-C4-OBn can be used in the synthesis of the PROTAC SGK3 degrader-1 . PROTAC SGK3 degrader-1 is a potent SKG3 degrader based on PROTAC[1][2].

[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 5. [2]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.