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STOCK2S 26016
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
STOCK2S 26016图片
CAS NO:332922-63-1
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
STOCK2S 26016 是一种 WNK 信号抑制剂。
Cas No.332922-63-1
Canonical SMILESNC1=C2C(C=CC(OCC)=C2)=NC3=C1C=CC(NCC4=CC=CO4)=C3
分子式C20H19N3O2
分子量333.38
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Lysine deficient protein kinase (WNK) signaling inhibitor (IC50 = 16 μM). Inhibits binding of WNK1 and WNK4 to SPAK and phosphorylation of downstream transporters, NKCC1 and NCC, in mouse vascular smooth muscle and distal convoluted tubule cell cultures exposed to hypotonic shock, respectively.

Mori et al (2013) Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy. Biochem.J. 455 339 PMID:23981180