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Pomalidomide-C7-COOH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pomalidomide-C7-COOH图片
CAS NO:2225940-51-0
包装与价格:
包装价格(元)
25mg电议
100mg电议
500mg电议

产品介绍
Pomalidomide-C7-COOH是一种合成的E3连接酶配体-linker偶联物,是PROTACBCL-XL降解剂合成的中间体。
Cas No.2225940-51-0
别名泊马度胺4'-烷基C7-酸
Canonical SMILESO=C(O)CCCCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
分子式C21H25N3O6
分子量415.44
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders[1].

[1]. Zhang X, et, al. Discovery of PROTAC BCL-X L degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15; 192: 112186.