您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > SBFI-26
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
SBFI-26
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1541207-06-0
包装:5 mg
市场价:9850元

产品介绍

产品描述

SBFI-26 is a selective and competitive fatty acid binding proteins FABP5 and FABP7 inhibitor(FABP5 and FABP7 with Kis of 0.9 μM and 0.4 μM, respectively), with anti-nociceptive and anti-inflammatory effects.

体外活性

SBFI-26 binds to the canonical ligand-binding pocket of FABP5[1],and cellular AEA accumulation significantly inhibited by SBFI-26[2].

体内活性

carrageenan-induced thermal hyperalgesia and paw edema significantly reduced by SBFI-26 (20 mg/kg, i.p.)[2]. SBFI-26 produces anti-inflammatory and antinociceptive effects in mice[2].

Cas No.

1541207-06-0

分子式

C28H22O4

分子量

422.47

储存和溶解度

DMSO:100 mg/mL (236.70 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years