SBFI-26 is a selective and competitive fatty acid binding proteins FABP5 and FABP7 inhibitor(FABP5 and FABP7 with Kis of 0.9 μM and 0.4 μM, respectively), with anti-nociceptive and anti-inflammatory effects.

SBFI-26 binds to the canonical ligand-binding pocket of FABP5[1],and cellular AEA accumulation significantly inhibited by SBFI-26[2].

carrageenan-induced thermal hyperalgesia and paw edema significantly reduced by SBFI-26 (20 mg/kg, i.p.)[2]. SBFI-26 produces anti-inflammatory and antinociceptive effects in mice[2].

1541207-06-0

C28H22O4

422.47

DMSO:100 mg/mL (236.70 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years