Spaglumic acid acetate 是一种在脑中以毫摩尔浓度存在的神经肽。

Spaglumic acid acetate is a neuropeptide found in millimolar concentrations in brain.

Spaglumic acid acetate is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. Spaglumic acid acetate is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes. The levels of Spaglumic acid acetate and the activity of carboxypeptidase II are altered in a regionally specific fashion in several neuropsychiatric disorders[1].

C13H20N2O10

364.31

Spaglumic acid acetate（3106-85-2 Free base）;Isospaglumic acid acetate

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years