| CAS NO: | 1127252-92-9 |
| 包装: | 1mg |
| 市场价: | 4158元 |
| Cas No. | 1127252-92-9 |
| 别名 | 普拉格雷杂质5,PCR 4099-d5 |
| Canonical SMILES | CC(OC1=CC2=C(S1)CCN(C(C(C3([2H])C([2H])([2H])C3([2H])[2H])=O)C4=CC=CC=C4F)C2)=O |
| 分子式 | C20H15D5FNO3S |
| 分子量 | 378.5 |
| 溶解度 | Chloroform: slightly soluble,Methanol: slightly soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Prasugrel-d5is intended for use as an internal standard for the quantification of prasugrel by GC- or LC-MS. Prasugrel is a prodrug form of the platelet purinergic P2Y12receptor antagonist R-99224.1Prasugrel (0.3 and 3 mg/kg) inhibitsex vivowashed platelet aggregation in rat platelet rich-plasma.2In vivo, prasugrel prevents thrombus formation (ED50= 0.68 mg/kg) and increases tail bleeding time in rats. Formulations containing prasugrel have been used in the prevention of blood clots. 1.Sugidachi, A., Asai, F., Yoneda, K., et al.Antiplatelet action of R-99224, an active metabolite of a novel thienopyridine-type Gi-linked P2T antagonist, CS-747Br. J. Pharmacol.132(1)47-54(2001) 2.Sugidachi, A., Asai, F., Ogawa, T., et al.The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist propertiesBr. J. Pharmacol.129(7)1439-1446(2000) |
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