WAY-213613 hydrochloride 是一个有效，选择性的，非底物再摄取GLT-1/EAAT2抑制剂，具有有效的 EAAT2 抑制活性，IC50值为 85 nM，它是阐明 EAAT2 功能的潜在工具,可用于中枢神经系统的研究。

WAY-213613 hydrochloride is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC 50 of 85 nM. WAY-213613 hydrochloride inhibits EAAT1 and EAAT3 with IC50 values of 5 and 3.8 microM, respectively. WAY-213613 hydrochloride shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function and can be used for the research of central nervous system [1] [2].

2450268-84-3

C16H14BrClF2N2O4

451.65

WAY-213613 hydrochloride (868359-05-1 free base)

DMSO:49 mg/mL (108.49 mM),warming and heat to 80°C
H2O:< 0.1 mg/mL (insoluble)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years