LinrodoSTAT 是选择性的、不可逆的吲哚胺 2,3-双加氧酶 1 (IDO1) 抑制剂，能够有效抑制IDO1-HEK293 细胞，其IC50=1.1 nM。它在晚期癌症中具有良好的药理特性。

BMS-986205 is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.

BMS-986205 shows potent inhibition of kynurenine production in IDO1-HEK293 cells (IC50: 1.1 nM) but not in TDO-HEK293 cells[1].

1923833-60-6

C24H24ClFN2O

410.91

BMS-986205

DMSO:25 mg/mL
H2O:Insoluble
Ethanol:15 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years