CAS NO: | 155584-74-0 |
规格: | ≥98% |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
Molecular Weight (MW) | 262.74 |
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Formula | C13H15ClN4 |
CAS No. | 155584-74-0 |
Storage | -20℃ for 3 years in powder form |
-80℃ for 2 years in solvent | |
Solubility (In vitro) | DMSO: 21 mg/mL (79.9 mM) |
Water: <1 mg/mL | |
Ethanol: 61 mg/mL (232.2 mM) | |
SMILES | CN1CCN(CC1)C2=NC3=CC=CC=C3N=C2Cl |
Synonyms | VUF 10166; VUF-10166; VUF10166; |
In Vitro | In vitro activity: VUF10166 shows low activity to 5-HT3AB receptor with Ki of 22 nM. VUF10166 may be used to can distinguish between 5-HT3A and 5-HT3AB receptors. VUF10166 has no activity to α7 nACh receptor. VUF10166 also acts as a partial agonist at 5-HT3A receptors with EC50 of 5.2 μM, which shows that VUF10166 is unlikely to bind in the receptor pore. |
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In Vivo | |
Animal model | |
Formulation & Dosage | |
References | J Pharmacol Exp Ther. 2012 May;341(2):350-9. |