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VUF 10166
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
VUF 10166图片
CAS NO:155584-74-0
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)262.74
FormulaC13H15ClN4
CAS No.155584-74-0
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 21 mg/mL (79.9 mM)
Water: <1 mg/mL
Ethanol: 61 mg/mL (232.2 mM)
SMILESCN1CCN(CC1)C2=NC3=CC=CC=C3N=C2Cl
SynonymsVUF 10166; VUF-10166; VUF10166;
实验参考方法
In Vitro

In vitro activity: VUF10166 shows low activity to 5-HT3AB receptor with Ki of 22 nM. VUF10166 may be used to can distinguish between 5-HT3A and 5-HT3AB receptors. VUF10166 has no activity to α7 nACh receptor. VUF10166 also acts as a partial agonist at 5-HT3A receptors with EC50 of 5.2 μM, which shows that VUF10166 is unlikely to bind in the receptor pore.

In Vivo
Animal model
Formulation & Dosage
References

J Pharmacol Exp Ther. 2012 May;341(2):350-9.