您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Fmoc-NH-PEG6-CH2CH2COOH
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Fmoc-NH-PEG6-CH2CH2COOH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fmoc-NH-PEG6-CH2CH2COOH图片
CAS NO:882847-34-9
包装与价格:
包装价格(元)
100mg电议
500mg电议
1 g电议

产品介绍
Fmoc-NH-PEG6-CH2CH2COOH是一种可降解的ADClinker,用于抗体药物偶联物(ADC)合成。
Cas No.882847-34-9
别名5,8,11,14,17,20-六氧杂-2-氮杂二十三碳二酸1-(9H-芴-9-基甲基)酯
Canonical SMILESO=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCOCCOCCC(O)=O
分子式C30H41NO10
分子量575.65
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fmoc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.