CAS NO: | 1623791-99-0 |
包装 | 价格(元) |
100mg | 电议 |
500mg | 电议 |
Cas No. | 1623791-99-0 |
别名 | 叠氮-八聚乙二醇-丙酸叔丁酯 |
Canonical SMILES | O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] |
分子式 | C23H45N3O10 |
分子量 | 523.62 |
溶解度 | DMSO: 200 mg/mL (381.96 mM) |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Azido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. Garofalo, Antonio, et al. Efficient synthesis of small-sized phosphonated dendrons: potential organic coatings of iron oxide nanoparticles. New Journal of Chemistry (2014), 38(11), 5226-5239. |