Hyodeoxycholic acid 是由肠道菌群在小肠中形成的次级胆汁酸,是TGR5 (GPCR19)的激动剂, CHO 细胞中的EC50=31.6 μM。它已用于研究高胆固醇血症的治疗。
产品描述
Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
Cas No.
83-49-8
分子式
C24H40O4
分子量
392.58
别名
HDCA;α-Hyodeoxycholic Acid;NSC 60672;猪去氧胆酸
储存和溶解度
DMSO:72 mg/mL (183.4 mM)
Ethanol:72 mg/mL (183.4 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years