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DBCO-PEG4-Biotin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
DBCO-PEG4-Biotin图片
CAS NO:1255942-07-4
包装:5mg
市场价:2835元

产品介绍
DBCO-PEG4-Biotin是一种含生物素基团和4个PEG的azadibenzocyclooctyne-biotin衍生物。DBCO-PEG4-Biotin是一种用途广泛的生物素酰化试剂，能通过无铜催化烷基叠氮化反应(SPAAC)将生物素的一部分引入叠氮标记的生物分子中。
Cas No.1255942-07-4
别名生物素-PEG4-DBCO
Canonical SMILESO=C(NCCOCCOCCOCCOCCC(NCCC(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)=O)=O)CCCC[C@@H]4SC[C@]([C@]4([H])N5)([H])NC5=O
分子式C39H51N5O8S
分子量749.92
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction[1].

The alkyne group can react with azide moiety in copper-free Click Chemistry reaction to form a stable triazole linkage.

[1]. Hammink R, et al. Affinity-Based Purification of Polyisocyanopeptide Bioconjugates. Bioconjug Chem. 2017 Oct 18;28(10):2560-2568.