Tinoridine hydrochloride 是非甾体抗炎药，具有显著的自由基清除和抗过氧化物特性。

Tinoridine (Y-3642) is a non-steroidal anti-inflammatory drug. Tinoridine (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxide formation and renin release induced by 50 μM ascorbic acid in the renin granule fraction. On the other hand, indomethacin, hydrocortisone, and prednisolone, which had no ability to inhibit the lipid peroxidation in the renin granule fraction, did not influence the release of renin from the granules. These results suggest that tinoridine suppresses renin release by inhibiting the oxidative disintegration of membranes of renin granules.

25913-34-2

C17H21ClN2O2S

352.88

Nonflamin;盐酸替诺立定;Y-3642 hydrochloride

DMSO:51 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years