您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Ebselen
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Ebselen
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ebselen图片
CAS NO:60940-34-3
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
25 mg电议
100 mg电议
200 mg电议

产品名称
依布硒
CCG-39161
PZ-51
SPI-1005
产品介绍
Ebselen 是一种谷胱甘肽过氧化物酶模拟物,是电压依赖性钙通道阻断剂。它抑制Mpro 和COVID-19病毒,是HIV-1衣壳 CTD 二聚化的抑制剂,具有抗炎、抗癌和抗氧化活性。

产品描述

Ebselen is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS). In addition, this agent inhibits the activity of a variety of enzymes including nitric oxide synthase (NOS), 5-lipoxygenase, cyclooxygenase, protein kinase C (PKC), NADPH oxidase and gastric H+/K+-ATPase. Furthermore, ebselen may be neuroprotective due to its ability to neutralize free radicals upon NMDA receptor activation thus, reducing lipoperoxidation mediated by glutamate-induced excitotoxicity.

Cas No.

60940-34-3

分子式

C13H9NOSe

分子量

274.192

别名

依布硒;CCG-39161;PZ-51;SPI-1005

储存和溶解度

H2O:Insoluble
DMSO:100 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years