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Licoflavone A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Licoflavone A图片
CAS NO:61153-77-3
包装与价格:
包装价格(元)
1 mg电议
5 mg电议

产品介绍
Licoflavone A 是分离自甘草根的黄酮类化合物,可以抑制酪氨酸磷酸酶 1B 的活性,IC50为 54.5 μM。

产品描述

Licoflavone A is a natural product isolated from the roots of Glycyrrhiza uralensis.

体外活性

Two new 2-arylbenzofurans, glycybenzofuran (1) and cyclolicocoumarone (2), together with 10 known flavonoids including licocoumarone (3), glycyrrhisoflavone (4), glisoflavone (5), cycloglycyrrhisoflavone (6), isoliquiritigenin (7), Licoflavone A (8), apigenin (9), isokaempferide (10), glycycoumarin (11), and isoglycycoumarin (12), were isolated from the roots of Glycyrrhiza uralensis and their structures were determined by extensive spectroscopic analyses. Compounds 1 and 5 showed significant protein tyrosine phosphatase-1B (PTP1B) inhibitory activity in vitro with the IC50 values of 25.5 and 27.9 μM, respectively.

Cas No.

61153-77-3

分子式

C20H18O4

分子量

322.35

储存和溶解度

H2O:< 0.1 mg/mL (insoluble)
DMSO:100 mg/mL (310.22 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years