Nobiletin 是一种来自柑橘皮的聚甲氧基黄酮，是RORs激动剂，可改善记忆力丧失。它可降低分化的 C2C12 肌管中的ROS水平，并具有抗炎，抗癌，抗血管生成，抗增殖，抗转移和诱导细胞凋亡作用。

Nobiletin is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa).

LD50: 780 mg/kg (i.g.). [4]

478-01-3

C21H22O8

402.4

川陈皮素;Hexamethoxyflavone;川皮苷

H2O:<1 mgml
Ethanol:3 mg/mL (7.45 mM)
DMSO:75 mg/mL (186.4 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years