(E)-3PO 是一种 PFKFB3(6-phosphofructo-2-kinase/fructose-2, 6-bisPhosphatase)抑制剂。
产品描述
(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.
激酶实验
Human sRAGE is immobilized (10 μg/mL) overnight at 4°C in 96-well microtiter plates and blocked with 3% bovine serum albumin. 125I-labeled Aβ40, HMGB1, or S100B at 5 nM in the absence and presence of various concentrations of FPS2 or FPS-ZM1 (10 to 1,000 nM) is added to the wells containing immobilized sRAGE and incubated for 1 hour at room temperature in PBS. Wells are washed with cold PBS to remove unbound radiolabeled ligands, and the radioactivity is analyzed[1].
Cas No.
13309-08-5
分子式
C13H10N2O
分子量
210.23
别名
3PO
储存和溶解度
DMSO:>10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years