Ac-CoA Synthase Inhibitor1 是一种可逆的醋酸盐依赖性乙酰辅酶 A 合成酶 2 抑制剂，IC50为 0.6 μM，可抑制呼吸道合胞病毒。

ACSS2 inhibitor is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2).

This quinoxaline compound inhibits the ability of HepG2 cells to incorporate [14C]acetate into lipids with IC50 = 6.8 μM. The quinoxaline is also able to inhibit HepG2 utilization of [14C]acetate for histone acetylation with IC50 = 5.5 μM.

508186-14-9

C20H18N4O2S2

410.51

ACSS2 inhibitor

H2O:<1 mgml
DMSO:28 mg/mL (68.2 mM)
Ethanol:2 mg/mL (4.87 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years