12-O-MethylcarNOSic acid 是分离自小叶丹参的丙酮提取物的一种二萜肉桂酸，可抑制 5α-还原酶 (5α-Reductase) 活性，IC50为 61.7 μM。它抑制 LNCaP 细胞的增殖。它具有抗微生物活性、抗氧化和抗癌活性。

12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM.12-O-Methylcarnosic acid has antioxidant activity, it is effective preventing gastric lesions. 12-O-Methylcarnosic acid can suppress melanin production with downregulation of tyrosinase expression in HMV-II melanoma cells.12-O-Methylcarnosic acid may have anti-diabetic activity, it is able to significantly activate peroxisome proliferator-activated receptor (PPAR)γ.

62201-71-2

C21H30O4

346.46

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years