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Gonadorelin Acetate(33515-09-2 free base)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Gonadorelin Acetate(33515-09-2 free base)图片
CAS NO:71447-49-9
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议

产品名称
Gonadorelin Acetate
Luteinizing Hormone Releasing Hormone (LH-RH)
Luteinizing Hormone Releasing Hormone (LH-RH), human
醋酸戈那瑞林
产品介绍
Gonadorelin Acetate (33515-09-2 free base) 是下丘脑神经肽,在控制生殖功能中起关键作用。

产品描述

Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.

体外活性

Luteinizing Hormone Releasing Hormone (LH-RH), also called gonadotropin-releasing hormone (GnRH), is the primary link between the brain, the pituitary and gonadal function, and has a key role in vertebrate reproduction. The endocrine actions of Luteinizing Hormone Releasing Hormone (LH-RH) and its analogs are mediated by high-affinity membrane receptors for LHRH on pituitary gonadotrophs. LHRH is expressed,together with its receptors,in hormonerelated tumors such as prostate cancer,to act as a local autocrine/paracrine growth inhibitory factor. In prostate cancer cells,the LHRH receptor is coupled to the Gi-cAMP pathway to inhibit cell proliferation.

体内活性

Luteinizing Hormone Releasing Hormone treatment advances the timing of vaginal opening by 5 days, which is used as an initial indicator for the time of puberty.

动物实验

Rat:Immature female Sprague-Dawley rats receive either 50 ng Luteinizing Hormone Releasing Hormone (LH-RH)/kg BW or 20 mg NMA/kg BW in a 10% dextrose, 0.9% NaCl solution, while controls receive only vehicle. After completion of the treatment, rats are examined daily for vaginal opening.

Cas No.

71447-49-9

分子式

C59H83N17O17

分子量

1302.415

别名

Gonadorelin Acetate;Luteinizing Hormone Releasing Hormone (LH-RH);Luteinizing Hormone Releasing Hormone (LH-RH), human;醋酸戈那瑞林

储存和溶解度

H2O:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years