DIPQUO hydrochloride是一种骨标记碱性磷酸酶 (ALP) 激活剂，在 C2C12 细胞中作用的 EC50 值为 6.27 μM。DIPQUO hydrochloride通过激活 p38 MAPK-β 促进小鼠和人类的成骨细胞分化。

DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.

ALP activity was measured using a fluorescent emission assay as a reporter for enzymatic digestion of ALP substrate in lysates derived from C2C12 myoblasts, DIPQUO shows EC50 of 6.27 μM[1].

T11048L

C20H18ClN3O

351.83

DIPQUO hydrochloride(1269365-82-3 Free base)

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years