Metformin 是一种 AMP 活化蛋白激酶激活剂，可通过提高胰岛素敏感性和减少肠道对葡萄糖的吸收来改善血糖控制。它可透过血脑屏障，诱导自噬。

Metformin is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.

Metformin is a first-line drug for the treatment of type 2 diabetes (T2D) and is often prescribed in combination with other drugs to control a patient's blood glucose level and achieve their HbA1c goal.

657-24-9

C4H12ClN5

129.167

甲福明;1,1-Dimethylbiguanide;二甲双胍

DMSO:26 mg/mL (201.3 mM)
H2O:26 mg/mL (201.3 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years