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Acid-PEG2-SS-PEG2-acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Acid-PEG2-SS-PEG2-acid图片
CAS NO:1807539-10-1
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Acid-PEG2-SS-PEG2-acid是一种可降解(cleavable)的含4个单元PEG的ADClinker,可用于合成抗体偶联药物(ADC)。
Cas No.1807539-10-1
Canonical SMILESO=C(O)CCOCCOCCSSCCOCCOCCC(O)=O
分子式C14H26O8S2
分子量386.48
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Acid-PEG2-SS-PEG2-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.