| CAS NO: | 90458-75-6 |
| 包装: | 500mg |
| 市场价: | 450元 |
| Cas No. | 90458-75-6 |
| 别名 | 依茨舒二钠 |
| Canonical SMILES | O=[S](CC(C1=O)(CCC2/C1=C/C(C=C3)=CC=C3/C=C(C4=O)/C(CCC45C[S](=O)(O[Na])=O)C5(C)C)C2(C)C)(O[Na])=O |
| 分子式 | C28H32Na2O8S2 |
| 分子量 | 606.66 |
| 溶解度 | DMSO : 50 mg/mL (82.42 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Ecamsule disodium is a broad-spectrum UVA filter that can be used in sunscreen product. Ecamsule reduces biological damage caused by solar radiation such as pyrimidine dimer formation, p53 protein accumula-tion, or collagenase 2 expression[1][2]. Ecamsule is a broad-spectrum UVA-absorber with maximum absorbance at 344 nm[1].Wild-type Fibs E6/E7 cells are more sensitive towards Ecamsule (200-1600 µM) treatment. In the fibroblasts, Ecamsule counteractes UV and AAPH induced ROS-formation. In addition, basal ROS levels are reduced. The effects are dose-dependent, reaching a maxi-mum ROS reduction by 25.7% at the highest tested concentration of 1600 µM in the UV-setting. With the same concentration of Ecamsule, oxidative stress that had been trigged by AAPH is reduced by 10.8% and basal levels are attenuated by 16.9%. Ecamsule increases the viability at the highest applied concentration of 1600 µM in the AAPH-treated cells[1]. References: |
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