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DMT-2'Fluoro-DG(IB)Amidite
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
DMT-2'Fluoro-DG(IB)Amidite图片
CAS NO:144089-97-4
包装:100mg
市场价:450元

产品介绍
DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) 是一种可用于制备 4'-modified 2'-deoxy-2'-fluorouridine 的核苷。
Cas No.144089-97-4
别名5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-脱氧-2'-氟-N-(2-甲基-1-氧代丙基)鸟苷3'-[2-氰基乙基N,N-二异丙基氨基亚磷酸酯],2'-F-ibu-dG Phosphoramidite
Canonical SMILESCC(C)N(C(C)C)P(OCCC#N)O[C@@H]([C@H]([C@@](N1C2=C(C(N=C(N2)NC(C(C)C)=O)=O)N=C1)([H])O3)F)[C@H]3COC(C4=CC=C(C=C4)OC)(C5=CC=CC=C5)C6=CC=C(C=C6)OC
分子式C44H53FN7O8P
分子量857.91
溶解度DMSO : 100 mg/mL (116.56 mM)
储存条件4℃, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine[1].

References:
[1]. Elise Malek-Adamian, et al. 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J Am Chem Soc. 2017 Oct 18;139(41):14542-14555.