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NH2-PEG6-CH2CH2COOH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NH2-PEG6-CH2CH2COOH图片
CAS NO:905954-28-1
包装:100mg
市场价:900元

产品介绍
NH2-PEG6-CH2CH2COOH 是一种可降解 (cleavable) 的 6 单元 PEG 类 ADC linker,用于抗体偶联药物 (ADC) 的合成。NH2-PEG6-CH2CH2COOH 也是一种基于 PEG 的 PROTAC linker,可用于 PROTAC 的合成。
Cas No.905954-28-1
别名氨基-六聚乙二醇-羧酸
分子式C15H31NO8
分子量353.41
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

NH2-PEG6-CH2CH2COOH is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[1]. Jaume Pons, et al. Engineered polypeptide conjugates and methods for making thereof using transglutaminase. US20130230543A1.