CAS NO: | 2387524-59-4 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Cas No. | 2387524-59-4 |
分子式 | C16H11FN2O2S |
分子量 | 314.33 |
溶解度 | DMSO : 125 mg/mL (397.67 mM; Need ultrasonic) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | NF-κβ activator 1 is a potent NF-κβ activator with an EC50 of 0.9 μM. NF-κβ activator 1 induces superoxide dismutase (SOD)2 mRNA expression[1]. NF-κβ activator 1 (compound 32) (1 μM; 6 hours) induces SOD2 mRNA expression in SH-SY5Y neuroblastoma cells[1]. [1]. Mathew B, et al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-?B activators for the treatment of ALS [published online ahead of print, 2020 Oct 22]. Eur J Med Chem. 2020;112952. |