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NF-κβ activator 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NF-κβ activator 1图片
CAS NO:2387524-59-4
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
NF-κβ activator 1 是一种有效的 NF-κβ 激活剂,EC50 为 0.9 μM,NF-κβ activator 1 诱导超氧化物歧化酶 (SOD)2 mRNA表达。
Cas No.2387524-59-4
分子式C16H11FN2O2S
分子量314.33
溶解度DMSO : 125 mg/mL (397.67 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

NF-κβ activator 1 is a potent NF-κβ activator with an EC50 of 0.9 μM. NF-κβ activator 1 induces superoxide dismutase (SOD)2 mRNA expression[1].

NF-κβ activator 1 (compound 32) (1 μM; 6 hours) induces SOD2 mRNA expression in SH-SY5Y neuroblastoma cells[1].

[1]. Mathew B, et al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-?B activators for the treatment of ALS [published online ahead of print, 2020 Oct 22]. Eur J Med Chem. 2020;112952.