Sesamol 是芝麻油的主要成分,具有抗氧化和抗肿瘤活性。它是一种自由基清除剂,在 DPPH 实验中,IC50为 5.95±0.56 μg/mL。
产品描述
Sesamol could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 signaling and blocking the NF-κB and MAPK signaling pathways and inhibits melanin biosynthesis by down-regulating tyrosinase activity and melanin production via regulation of gene expression of melanogenesis-related proteins through modulation of MITF activity, which promotes phosphorylation of p38 and JNK in melan-a cells.
Cas No.
533-31-3
分子式
C7H6O3
分子量
138.122
别名
1,3-Benzodioxol-5-ol;芝麻酚;3,4-Methylenedioxyphenol
储存和溶解度
Chloroform, Dichloromethane, Ethyl Acetate:Soluble
DMSO:25 mg/mL(181 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years