PFI3是一种选择性,可渗透细胞的SMARCA2/4溴结构域抑制剂,Kd值为89 nM,可延迟和预防乳腺癌。
产品描述
PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.
体外活性
PFI-3 shows a significant selectivity for PB1(5) and SMARCA2/4 over 36 other tested kinases. [1]
Cas No.
1819363-80-8
分子式
C19H19N3O2
分子量
321.38
别名
PFI 3
储存和溶解度
DMSO:32.1 mg/mL(100 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years