1-Naphthyl PP1 是选择性的Src家族激酶抑制剂,能够抑制 v-Src (IC50:1.0 μM)、c-Fyn (IC50:0.6 μM)、c-Abl (IC50:0.6 μM)、CDK2 (IC50:18 μM) 和 CaMK II (IC50:22 μM)。
产品描述
1-Naphthyl PP1 is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)
Cas No.
221243-82-9
分子式
C19H19N5
分子量
317.396
别名
4 -氨基- 1 -叔丁基- 3 -(1' -萘基)吡唑并[3,4 - D]嘧啶;1-NA-PP 1
储存和溶解度
DMSO:12 mg/mL (37.8 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years