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TLR4-IN-C34-C2-COOH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TLR4-IN-C34-C2-COOH图片
CAS NO:1159408-54-4
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
500mg电议
1 g电议

产品介绍
TLR4-IN-C34-C2-COOH 是一种含有 TLR4 抑制剂 TLR4-IN-C34 的连接子。TLR4-IN-C34 抑制肠细胞和巨噬细胞中的 TLR4,减少内毒素血症和坏死性小肠结肠炎小鼠模型的全身炎症。
Cas No.1159408-54-4
别名5-[[(2R,3R,4R,5R,6R)-3-乙酰氨基-4,5-二乙酰氧基-6-(乙酰氧基甲基)-2-四氢吡喃基]氧基]戊酸
分子式C19H29NO11
分子量447.43
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

TLR4-IN-C34-C2-COO is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis[1].

[1]. Neal MD, et al. Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One. 2013;8(6):e65779. Published 2013 Jun 12.